Autologous hematopoietic stem cell transplantation (auto-HSCT) in children in Poland: 2021 indications and practice

Unlike in adults, the number of pediatric autologous hematopoietic stem cell transplants (HSCT) has decreased last years. This is because changing indications for this type treatment and new therapies available recent Polish HSCT centers have followed published recommendations Pediatric Hematopoietic Stem Cell Transplantation Group, which are generally based on European Society Blood Marrow indications. Differences observed obtaining cells from children compared to adults terms timing scheduled harvest technical aspects harvesting procedure. As a result, populations involves more medical professionals, requires time financial resources adults. transplantation neuroblastoma Ewing’s sarcoma confirmed efficacy. Autologous young established transplant procedure now increasingly used apheresis lymphocytes approved CAR-T relapsed/resistant leukemia lymphoma. Recent studies suggest that cell-based immunotherapy potential refractory or relapsed solid tumors.